| 摘要 |
Disclosed are fungicidal 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives as represented by the general formula I, wherein: R1 is H, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted phenyl or benzyl, optionally substituted biphenyl or naphthyl, -(CHR6)mOR7, -C(=O)R8, -C(=S)R8, -S(O)2R8, -C(=O)OR8, -C(=S)OR8, -(CHR6)mN(R9)R10, -C(=O)N(R9)R10 or -C(=S)N(R9)R10; R2 is H or optionally substituted alkyl; alternatively R1 and R2 may be taken together to form =CR11N(R12)R13; R3 is -C(=O)OR8 or -C(=S)OR8; and wherein the other substituents are as defined herein. Representative compounds include 4-(dimethylarnino-methyleneamino)-5-fluoro-2-oxo-2H-pyrimidine-1-carboxylic acid 2,2-dimethyl-propyl ester, benzyI 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate, ethyI 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate, isopropyI 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate, phenyI 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate, O-phenyI 4-amino-5-fluoro-2-oxopyrimidine-1(2H)-carbothioate and pentyI 4-(benzyl(methyl)amino)-5-fluoro-2-oxopyrimidine-1(2H)-carboxylate. Also disclosed is a composition for the control of a fungal pathogen including a compound as defined above or and a phytologically acceptable carrier material. |
