Antimicrobial compounds and methods of making and using the same

摘要

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These fused heterocycle compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals. Fused heterocycle core structures present in the compounds include: pyrrolo[2,3-d]pyrimidin-2-ol, imidazo[1,2-a]pyrimidin-7-one, pyrimido[1,2-a]benzimidazol-2-one and pyrimido[1,2-a]indol-2-one