PROCESS FOR PRODUCING A PARTICULATE COMPOSITION COMPRISING ANHYDROUS CRYSTALLINE 2-O-ALPHA-D-GLUCOSYL-L-ASCORBIC ACID

摘要

The invention provides a process for enabling the production of a particulate composition containing anhydrous crystalline ascorbic acid 2-glucoside that does not significantly cake even when the production yield of ascorbic acid 2-glucoside does not reach 35% by weight. The process for producing a particulate composition containing anhydrous crystalline ascorbic acid 2-glucoside, which comprises allowing a CGTase to act on a solution containing either liquefied starch or dextrin and L-ascorbic acid and then allowing a glucoamylase to act on the resulting solution to obtain a solution with an ascorbic acid 2-glucoside production yield of at least 27%, purifying the obtained solution to increase the ascorbic acid 2-glucoside content to a level of over 86% by weight, precipitating anhydrous crystalline ascorbic acid 2-glucoside by a controlled cooling method or pseudo-controlled cooling method, collecting the precipitated anhydrous crystalline ascorbic acid 2-glucoside, and ageing and drying the collected anhydrous crystalline ascorbic acid 2-glucoside.

主权项

1. A process for producing a particulate composition comprising anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid, said process comprising the following steps (a) to (e):
(a) allowing a cyclomaltodextrin glucanotransferase to act on a solution comprising either liquefied starch or dextrin and L-ascorbic acid as materials, and then allowing a glucoamylase to act on the resulting solution to obtain a solution comprising 2-O-α-D-glucosyl-L-ascorbic acid in a 2-O-α-D-glucosyl-L-ascorbic acid production yield of at least 27% by weight; (b) purifying the resulting solution comprising 2-O-α-D-glucosyl-L-ascorbic acid to give a 2-O-α-D-glucosyl-L-ascorbic acid content of over 86% by weight, on a dry solid basis; (c) precipitating anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid from the purified solution with a 2-O-α-D-glucosyl-L-ascorbic acid content of over 86% by weight, on a dry solid basis, by a controlled cooling method or pseudo-controlled cooling method; (d) collecting the precipitated anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid; and (e) ageing, drying, and optionally pulverizing the collected anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid without dissolving and recrystallizing it to obtain a particulate composition comprising anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid which comprises 2-O-α-D-glucosyl-L-ascorbic acid in a content of, on a dry solid basis, over 98.0% by weight but below 99.9% by weight, and has a degree of crystallinity for anhydrous crystalline 2-O-α-D-glucosyl-L-ascorbic acid of at least 90%, when calculated based on the powder X-ray diffraction profile of the particulate composition.