发明名称 |
PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL |
摘要 |
The present invention provides novel process for preparation of olmesartan medoxomil (I) substantially free of olmesartan acid impurity (II) comprising, reacting trityl olmesartan medoxomil (III) with acid, filtering the precipitate of trityl alcohol, subjecting the filtrate to agitated thin film drying and recovering olmesartan medoxomil (I). |
申请公布号 |
US2014179930(A1) |
申请公布日期 |
2014.06.26 |
申请号 |
US201214237213 |
申请日期 |
2012.07.31 |
申请人 |
Firke Rajendra Vishwanath;Sisodia Ujjwal Komalsing;Bhangale Chandrakant Shriram;Shivdavkar Radhakrishna Bhikaji;Godbole Himanshu Madhav;Singh Girij Pal |
发明人 |
Firke Rajendra Vishwanath;Sisodia Ujjwal Komalsing;Bhangale Chandrakant Shriram;Shivdavkar Radhakrishna Bhikaji;Godbole Himanshu Madhav;Singh Girij Pal |
分类号 |
C07D405/14 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
1. A process for preparation of olmesartan medoxomil (I) comprising: a) reacting trityl olmesartan medoxomil (III) with an acid, b) filtering the precipitate of trityl alcohol, c) subjecting the filtrate to agitated thin film drying, and d) recovering olmesartan medoxomil (I). |
地址 |
Tarapur IN |