COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS

摘要

PROBLEM TO BE SOLVED: To provide: compounds for inhibiting Na/Hexchanger (NHE)-mediated antiport of sodium ions and hydrogen ions of useful for irritable bowel syndrome, kidney disease, and disorders associated with fluid retention or salt overload; and pharmaceutical compositions containing the compounds.SOLUTION: Provided are compounds represented by the specified compounds, and pharmaceutical compositions containing the compounds.