发明名称 |
VEGF-BINDING PROTEIN FOR BLOCKADE OF ANGIOGENESIS |
摘要 |
Provided are chimeric VEGF-binding proteins and nucleic acids (e.g., a vector) encoding chimeric VEGF-binding proteins, methods and host cells for producing these proteins and nucleic acids, and pharmaceutical compositions containing these proteins and nucleic acids. Also provided are methods of treating an angiogenic disease or disorder that include administering at least one of the chimeric VEGF-binding proteins or at least one of the nucleic acids (e.g., a vector) encoding a chimeric VEGF-bind ing protein. |
申请公布号 |
EP2744508(A1) |
申请公布日期 |
2014.06.25 |
申请号 |
EP20120826108 |
申请日期 |
2012.08.17 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE GENERAL HOSPITAL CORPORATION |
发明人 |
CARTER, BOB;LEE, JENG-SHIN;BULLAIN, SZOFIA S.;MULLIGAN, RICHARD C. |
分类号 |
A61K38/18;A61K39/395;A61P35/00;C07K14/515 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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