PIMARANE DITERPENES FROM ANISOCHILUS VERTICILLATUS

摘要

This invention discloses diterpenes class of novel compounds of general formula I from a novel source. More particularly the invention relates to extracts/fractions containing pimarane diterpenes from Anisochillus (Lamiaceae), useful for prevention, treatment, inhibition or controlling growth and proliferation of mycobacterial activity in mammals. The invention further relates to extracts, fractions standardized to diterpenes class of novel compounds useful for the treatment of cancers.

主权项

1. Compounds of general formula I wherein R1, R, R3 and R4 could be either α or β oriented. R1 and R3 is independently selected from the group consisting of —OH or the substituent R1 and R3 together form peroxide (—O—O—) linkage; R2 and R4 is independently selected from the group H or OH.