发明名称 COMPOSITION INCLUDING FUSION PROTEIN OR POLYPEPTIDE DERIVED FROM PROSAPOSIN TO BE APPLIED TO TRANSMEMBRANE DRUG DELIVERY SYSTEM
摘要 <p>PROBLEM TO BE SOLVED: To provide a method for delivering an active agent that is a pharmaceutical and/or an imaging factor within and/or through dermal, mucosal and other cellular membranes, and across the blood-brain barrier.SOLUTION: The present invention provides a delivery method using a composition containing liposome comprising a mixture of anionic long-chain lipids, neutral long-chain lipids, and neutral short-chain lipids, to which saposin C and other proteins, polypeptides and peptide analogs derived from saposin C are coupled, and an active agent contained within the liposome which is a biomolecule and/or organic molecules.</p>
申请公布号 JP2014111600(A) 申请公布日期 2014.06.19
申请号 JP20130257476 申请日期 2013.12.12
申请人 CHILDRENS HOSPITAL MEDICAL CENTER 发明人 QI XIAOYANG
分类号 A61K9/127;A61K38/00;A61K38/43;A61K45/00;A61K47/04;A61K47/12;A61K47/24;A61K49/00;A61K51/00;A61P3/00;A61P43/00 主分类号 A61K9/127
代理机构 代理人
主权项
地址