发明名称 |
Modified beta-lactamases and methods and uses related thereto |
摘要 |
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects. Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide. |
申请公布号 |
AU2011257092(C1) |
申请公布日期 |
2014.06.19 |
申请号 |
AU20110257092 |
申请日期 |
2011.05.17 |
申请人 |
SYNTHETIC BIOLOGICS, INC |
发明人 |
KOSKI, PERTTI;AIRAKSINEN, ULLA;VALIMAKI, KATJA |
分类号 |
C12N9/86;A61K38/46;A61P1/12;C12N1/21;C12N15/55;C12N15/75 |
主分类号 |
C12N9/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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