CONTROL SYSTEM AND METHOD FOR FLASH SEPARATION

摘要

A chromatography system may include: a first solvent supply operatively connected to a chromatography column; a second solvent supply operatively connected to the chromatography column; a controller operatively connected to the first and second solvent supplies for delivering a flow of a solvent system to an inlet for the chromatography column in accord with a predetermined solvent gradient, wherein the flow of the solvent system through the chromatography column will separate components from a sample composition; and a collection apparatus operatively connected to an outlet from the chromatography column for collecting designated portions of the solvent system flow exiting the column. The controller may determine a target sample mass as a function of chromatography column parameters.

主权项

1. A chromatography system, comprising:
a first solvent supply operatively connected to a chromatography column; a second solvent supply operatively connected to the chromatography column; a controller operatively connected to the first and second solvent supplies for delivering a flow of a solvent system to an inlet for the chromatography column in accord with a predetermined solvent gradient, wherein the flow of the solvent system through the chromatography column will separate components from a sample composition; and a collection apparatus operatively connected to an outlet from the chromatography column for collecting designated portions of the solvent system flow exiting the column; wherein the controller also determines a target sample mass as a function of chromatography column parameters.