Oral controlled release compositions comprising vitamin D compound and waxy carrier
摘要
A stable, controlled release formulation for oral dosing of vitamin D compounds is disclosed. The formulation is prepared by incorporating one or more vitamin D compounds into a solid or semi-solid mixture of waxy materials. Oral dosage forms can be prepared by melt-blending the components described herein and filling gelatin capsules with the formulation.
申请公布号
EP2481400(B1)
申请公布日期
2014.06.18
申请号
EP20120154573
申请日期
2008.04.25
申请人
CYTOCHROMA INC.;PROVENTIV THERAPEUTICS, LLC
发明人
BISHOP, CHARLES W.;TABASH, SAMIR P.;AGUDOAWU, SAMMY A.;WHITE, JAY A.;CRAWFORD, KEITH H.;MESSNER, ERIC J.;PETKOVICH, P. MARTIN