| 发明名称 |
PYRROLOPYRAZINE KINASE INHIBITORS |
| 摘要 |
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 申请公布号 |
KR20140074912(A) |
申请公布日期 |
2014.06.18 |
| 申请号 |
KR20147008471 |
申请日期 |
2012.08.27 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
CHEN SHAOQING;DE VICENTE FIDALGO JAVIER;HAMILTON MATTHEW MICHAEL;HERMANN JOHANNES CORNELIUS;KENNEDY SMITH JOSHUA;LI HONGJU;LOVEY ALLEN JOHN;LUCAS MATTHEW C.;LUK KIN CHUN THOMAS;LYNCH STEPHEN M.;O'YANG COUNDE;PADILLA FERNANDO;SCHOENFELD RYAN CRAIG;SIDDURI ACHYUTHARAO;SOTH MICHAEL;WANG CE;WOVKULICH PETER MICHAEL;ZHANG XIAOHU |
| 分类号 |
C07D487/04;A61K31/4985;A61K31/5025;A61P29/00 |
主分类号 |
C07D487/04 |
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