Biofilm-removing antimicrobial compositions and uses thereof

摘要

The present invention provides novel compositions comprising: (a) protamine sulfate and (b) benzalkonium chloride or a silver containing particle; or (a) sodium metaperiodate and (b) 5-fluorouracil or chlorhexidine and uses thereof for the preparation of devices, and in particular medical devices, susceptible to colonization by biofilm forming bacteria.

主权项

1. A composition for removing or reducing microbial biofilms, wherein the biofilm is caused by one or more of Pseudomonas aeruginosa, Staphylococcus epidermis, and Escherichia coli, comprising: (a) a sodium meta-periodate and (b) chlorhexidine.