发明名称 Method of making demineralized bone particles
摘要 Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles.
申请公布号 US8753689(B2) 申请公布日期 2014.06.17
申请号 US201314021179 申请日期 2013.09.09
申请人 Warsaw Orthopedic, Inc. 发明人 Morris John W.;Shimp Lawrence A.;Petersen Kenneth C.;Manrique Albert;Kaes David;Scarborough Nelson;Dowd Michael
分类号 A61K35/32 主分类号 A61K35/32
代理机构 Sorell Lenna & Schmidt LLP 代理人 Sorell Lenna & Schmidt LLP
主权项 1. A method of making demineralized bone particles, comprising: demineralizing whole bone, the whole bone comprising collagen fibers; and thereafter subdividing the demineralized bone by pressing the demineralized bone into demineralized bone particles comprising intact collagen fibers, wherein pressing the demineralized bone comprises applying a mechanical pressure to the demineralized bone from about 1,000 to about 40,000 psi.
地址 Warsaw IN US