| 发明名称 |
Chimeric West Nile/Dengue viruses |
| 摘要 |
The disclosure provides chimeric West Nile/Dengue viruses comprising non- coding regions, non-structural proteins, and a C protein from a West Nile virus and prM and E proteins from a Dengue virus. Also disclosed are methods of using the chimeric viruses in diagnosis of Dengue viral infection, assessment of candidate Dengue virus vaccine efficacy, and production of Dengue prM and E proteins. |
| 申请公布号 |
AU2009241354(B2) |
申请公布日期 |
2014.06.12 |
| 申请号 |
AU20090241354 |
申请日期 |
2009.04.27 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION |
发明人 |
KINNEY, CLAIRE Y. H.;BECK, ERIC THOMAS;KINNEY, RICHARD M. |
| 分类号 |
C12N15/40;A61K39/12;C07K14/18;C12N7/01 |
主分类号 |
C12N15/40 |
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