| 发明名称 |
HETEROARYL ALKYNE COMPOUND AND USE THEREOF |
| 摘要 |
<p>The present invention relates to the field of the chemical medicines, and in particular, to a compound with a Heteroaryl alkyne structure shown in formula I or pharmaceutically acceptable salts, isomers, solvate, crystal or prodrug thereof, pharmaceutical compositions containing there compounds and applications of these compounds or compositions in the medicine preparation. The compound of the present invention has a strong inhibiting effect on BCR-ABL kinase, and can be used for treating, for example, neoplastic diseases.</p> |
| 申请公布号 |
CA2891851(A1) |
申请公布日期 |
2014.06.05 |
| 申请号 |
CA20132891851 |
申请日期 |
2013.11.27 |
| 申请人 |
NANJING SANHOME PHARMACEUTICAL CO., LTD. |
发明人 |
WANG, YONG;ZHAO, LIWEN;ZHANG, DI;WU, FENG;BI, SHENG;GAO, YIPING;CHEN, HONGBIN;CHEN, HONGYAN;ZHANG, CANG;NAN, YANG;LIU, YANG |
| 分类号 |
C07D471/04;A61K31/4178;A61K31/4196;A61K31/4439;A61K31/496;A61K31/4985;A61P35/00;A61P35/02;C07D233/64;C07D233/92;C07D401/04;C07D401/14;C07D403/14;C07D487/04 |
主分类号 |
C07D471/04 |
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