发明名称 |
Method of promoting nucleic acid transfer |
摘要 |
Means for transferring efficiently a desired nucleic acid into a cell is provided.;The present invention comprises using a complex comprising a collagen or a collagen derivative, and a desired nucleic acid. |
申请公布号 |
US8742091(B2) |
申请公布日期 |
2014.06.03 |
申请号 |
US20020481511 |
申请日期 |
2002.06.20 |
申请人 |
Dainippon Sumitomo Pharma Co., Ltd.;Koken Co., Ltd.;National Cancer Center |
发明人 |
Terada Masaaki;Ochiya Takahiro;Aso Yu;Honma Kimi;Sano Akihiko;Nagahara Shunji |
分类号 |
C07H21/02;A61K38/17;C12N15/11 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical preparation for administration to a living body comprising a solution of an electrostatic complex consisting essentially of a double-stranded RNA and a water-soluble atelocollagen, wherein said complex facilitates the transfer of said double-stranded RNA to a target tissue or a target organ and said complex exhibits a major axis of 100 μm or less in length.
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地址 |
Osaka-Shi JP |