发明名称 Synthesis of lipoamide-grafted high molecular compound and method therefor
摘要 The present disclosure provides polymer compounds binding with lipoamide produced by the reaction of the primary amine group of lipoamide with the carboxy group of polysaccharide compounds such as chondroitin sulfates, carboxymethyl celluloses, or hyaluronic acids; functional compounds such as peptides, proteins, growth factors; or drugs; or biocompatible polymers such as poly(ethylene oxide), poly(vinyl alcohol), or poly(vinyl pyrrolidone). The present disclosure also provides their synthesis methods, products of hydrogels and films using the same as and methods for manufacturing the products.
申请公布号 US8742013(B2) 申请公布日期 2014.06.03
申请号 US20090608126 申请日期 2009.10.29
申请人 Seoul National University of Technology Center for Industrial Collaboration 发明人 Noh Insup;Jo Seongyeun;Kim Doyeon;Woo Junghoon
分类号 A61K38/18;A61K47/36;A61K47/38;C08B15/06;C08B37/02;C08B37/04;C08B37/08;C08B37/10 主分类号 A61K38/18
代理机构 代理人
主权项 1. A polymer generated by forming a covalent bond between the amide group of lipoamide and a carboxyl group of a compound selected from the group consisting of heparins, hyaluronic acids, carboxymethyl celluloses, dermatans, chitosans, dextrans, alginates, chondroitin sulfates, peptides, collagens, proteins, hormones, drugs, growth factors, poly(ethylene oxide), poly(vinyl alcohol), poly(vinyl pyrrolidone), polylactides, and polyglycolides; wherein lipoamide has the following chemical structure:
地址 Seoul KR