发明名称 |
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS |
摘要 |
<p>Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type (1) signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.</p> |
申请公布号 |
CA2892027(A1) |
申请公布日期 |
2014.05.30 |
申请号 |
CA20132892027 |
申请日期 |
2013.11.20 |
申请人 |
RQX PHARMACEUTICALS, INC. |
发明人 |
ROBERTS, TUCKER CURRAN;SMITH, PETER ANDREW;HIGUCHI, ROBERT I.;CAMPBELL, DAVID;PARASELLI, PRASUNA |
分类号 |
C07D245/04;A61K31/395;A61P31/04 |
主分类号 |
C07D245/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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