THROMBIN INHIBITORS

摘要

The invention includes substituted azetidinyl and pyrrolidinyl compounds, as thrombin inhibitors, for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation in a mammal. The compounds can be added to blood, blood products, or mammalian organs in order to effect the desired inhibitions.