发明名称 |
NEPRILYSIN INHIBITORS |
摘要 |
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds. |
申请公布号 |
SG11201401894X(A) |
申请公布日期 |
2014.05.29 |
申请号 |
SGX11201401894 |
申请日期 |
2012.11.01 |
申请人 |
THERAVANCE, INC. |
发明人 |
HUGHES, ADAM;FENSTER, ERIK;FLEURY, MELISSA;GENDRON, ROLAND;MORAN, EDMUND, J. |
分类号 |
A61K31/165;A61K31/215;A61P5/00;A61P9/00;C07C231/02;C07C233/56;C07C241/04;C07C243/30;C07C271/22;C07C317/40 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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