发明名称 NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
申请公布号 SG11201401894X(A) 申请公布日期 2014.05.29
申请号 SGX11201401894 申请日期 2012.11.01
申请人 THERAVANCE, INC. 发明人 HUGHES, ADAM;FENSTER, ERIK;FLEURY, MELISSA;GENDRON, ROLAND;MORAN, EDMUND, J.
分类号 A61K31/165;A61K31/215;A61P5/00;A61P9/00;C07C231/02;C07C233/56;C07C241/04;C07C243/30;C07C271/22;C07C317/40 主分类号 A61K31/165
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