Anti-p-selectin antibodies, a nucleic acid encoding the antibody, vector comprising the nucleic acid, a method for preparing the antibody and a pharmaceutical composition comprising it

摘要

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor Clq. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).