发明名称 |
PHOSPHORYLATED POLYOLS, PYROPHOSPHATES, AND DERIVATIVES THEREOF HAVING BIOLOGICAL ACTIVITY |
摘要 |
The present invention provides phosphorylated and pyrophosphate derivatives of polyols, and structural derivatives of these compounds, and provides pharmaceutical compositions comprising the same. The compounds and compositions disclosed herein have various biological activities, including for example, as allosteric effectors of hemoglobin and/or as kinase inhibitors. The present invention further provides methods for therapy in human or mammalian patients, and methods for synthesis of biologically active compounds and their intermediates. |
申请公布号 |
US2014142052(A1) |
申请公布日期 |
2014.05.22 |
申请号 |
US201313897113 |
申请日期 |
2013.05.17 |
申请人 |
NORMOXYS, INC.;UNIVERSITE DE STRASBOURG |
发明人 |
LEHN JEAN-MARIE;NICOLAU YVES CLAUDE;POTHUKANURI SRINIVASU;BROCKMAN ADAM;HEY JOHN;YU JEREMY |
分类号 |
C07F9/6564;A61K31/6615;A61K31/7028;A61K45/06 |
主分类号 |
C07F9/6564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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