发明名称 INHIBITORS OF INFLUENZA VIRUSES REPLICATION
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 US2014142119(A1) 申请公布日期 2014.05.22
申请号 US201314098867 申请日期 2013.12.06
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 CHARIFSON PAUL S.;CLARK MICHAEL P.;BANDARAGE UPUL K.;BETHIEL RANDY S.;COURT JOHN J.;DENG HONGBO;DAVIES IOANA;DUFFY JOHN P.;FARMER LUC J.;GAO HUAI;GU WENXIN;JACOBS DYLAN H.;KENNEDY JOSEPH M.;LEDEBOER MARK W.;LEDFORD BRIAN;MALTAIS FRANCOIS;PEROLA EMANUELE;WANG TIANSHENG;WANNAMAKER M. WOODS;BYRN RANDAL;ZHOU YI;LIN CHOA;JIANG MIN;JONES STEVEN;GERMANN URSULA A.;SALITURO FRANCESCO G.
分类号 C07D471/04 主分类号 C07D471/04
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