发明名称 |
MATERIALS AND METHODS FOR DIRECTING AN IMMUNE RESPONSE TO AN EPITOPE |
摘要 |
The present invention relates to compositions, kits, and methods useful for directing an immune response to an epitope of an antigen in a subject, by sensitizing the subject to the epitope and/or by tolerizing the subject to the epitope. The sensitizing method comprises co-administering to the subject the epitope and an immunoglobulin M (IgM) constant region (IgM Fc region). The tolerizing method comprises co-administering to the subject the epitope and an immunoglobulin G (IgG) constant region (IgG Fc region) to the subject. |
申请公布号 |
US2014140986(A1) |
申请公布日期 |
2014.05.22 |
申请号 |
US201113884177 |
申请日期 |
2011.11.08 |
申请人 |
SANTOS CARLOS F.;POPA-MCKIVER MIHAELA;MCCORD AMY M.;HIRSCHEL MARK;BIOVEST INTERNATIONAL, INC. |
发明人 |
SANTOS CARLOS F.;POPA-MCKIVER MIHAELA;MCCORD AMY M.;HIRSCHEL MARK |
分类号 |
A61K39/395;A61K39/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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