发明名称 |
Inhibitors of protein tyrosine kinase activity |
摘要 |
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions. |
申请公布号 |
US8729268(B2) |
申请公布日期 |
2014.05.20 |
申请号 |
US20090920676 |
申请日期 |
2009.02.27 |
申请人 |
MANNION MICHAEL;RAEPPEL STÉPHANE;CLARIDGE STEPHEN WILLIAM;GAUDETTE FRÉDÉRIC;ZHAN LIJIE;ISAKOVIC LJUBOMIR;SAAVEDRA OSCAR MARIO;UNO TETSUYUKI;KISHIDA MASASHI;VAISBURG ARKADII;METHYLGENE INC. |
发明人 |
MANNION MICHAEL;RAEPPEL STÉPHANE;CLARIDGE STEPHEN WILLIAM;GAUDETTE FRÉDÉRIC;ZHAN LIJIE;ISAKOVIC LJUBOMIR;SAAVEDRA OSCAR MARIO;UNO TETSUYUKI;KISHIDA MASASHI;VAISBURG ARKADII |
分类号 |
A61K31/4365;C07D513/04 |
主分类号 |
A61K31/4365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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