发明名称 AMINOCARBOXYLIC ACID DERIVATIVE AND MEDICINAL USE THEREOF
摘要 The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. (see formula I) wherein all symbols are described in the specification.
申请公布号 CA2591399(C) 申请公布日期 2014.05.20
申请号 CA20052591399 申请日期 2005.12.12
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 HABASHITA, HIROMU;KURATA, HARUTO;NAKADE, SHINJI
分类号 C07C229/14;A61K31/12;A61K31/166;A61K31/197;A61K31/215;A61K31/397;A61K31/4035;A61K31/41;A61K31/437;A61K31/4409;A61K31/4412;A61K31/4439;A61K31/4725;A61K31/55;A61K45/00;A61P1/04;A61P3/10;A61P7/00;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/04;A61P25/00;A61P29/00;A61P37/06;A61P43/00;C07C257/18;C07D205/04;C07D209/44;C07D211/22;C07D211/70;C07D211/74;C07D211/80;C07D223/16;C07D271/06;C07D401/04;C07D409/04;C07D413/04;C07D471/04;C07F5/04 主分类号 C07C229/14
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