SEVELAMER CARBONATE MEDICINAL TABLET COMPOSITION AND PREPARATION METHOD THEREOF

摘要

A sevelamer carbonate medicinal tablet composition and preparation method thereof, the sevelamer carbonate medicinal tablet composition comprising 60-95 parts by weight of sevelamer carbonate, 5-30 parts by weight of crospovidone, and 0.1-10.0 parts by weight of silicon dioxide; the tablet composition preparation method comprising the following steps: a), using a conventional method to mix the sevelamer carbonate with crospovidone; b), granulating the mixture obtained in step a; c), mixing the silicon dioxide with the granules obtained in step b to prepare a tablet; and d), using a water soluble coating material to coat a thin film on the tablet.