发明名称 |
Multivalent meningococcal polysaccharide-protein conjugate vaccine |
摘要 |
The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacteria Neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine. Purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y are chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains in children as well as adults. |
申请公布号 |
US8722062(B2) |
申请公布日期 |
2014.05.13 |
申请号 |
US20020054638 |
申请日期 |
2002.01.22 |
申请人 |
RYALL ROBERT P.;SANOFI PASTEUR, INC. |
发明人 |
RYALL ROBERT P. |
分类号 |
A61K39/05;A61K39/095;A01N43/04;A61K39/00;A61K39/02;A61K39/385;A61K47/48;A61P31/04;A61P43/00;C07H1/00 |
主分类号 |
A61K39/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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