Biological photo-receptors as directly light-controlled ion channels and their use

摘要

Use of a biological photoreceptor (A) as light-controlled ion channel for changing the ionic conductivity of a membrane in response to light. (A) comprises an apoprotein (I) covalently bound to a light-sensitive polyene (II), where (II) interacts with (I) and functions as a light-sensitive gate. - ACTIVITY : Ophthalmological. No details of tests for ophthalmological activity are given. - MECHANISM OF ACTION : Depolarization of retinal cells and thus induction of nerve impulses.