发明名称 |
METHOD FOR AMPLIFYING NK CELLS |
摘要 |
A technique is needed which can amplify NK cells in vitro and prepare optimum number of NK cells for the adoptive immunotherapy. A method for amplifying NK cells is provided which comprises steps of: preparing cell population which is comprised of NK cells, removing T cells from the cell population which is comprised of NK cells, and, after removal of T cells, cultivating the remaining cells in a medium supplemented with 2500 to 2831 IU/mL of IL-2. The method for amplifying NK cells of the present invention may comprise a step of removing hematopoietic progenitor cells from the cell population. The present invention provides a pharmaceutical composition for adoptive immunotherapy, comprising NK cells which are prepared by the amplifying method of the present invention. |
申请公布号 |
US2014120072(A1) |
申请公布日期 |
2014.05.01 |
申请号 |
US201214129143 |
申请日期 |
2012.06.20 |
申请人 |
YONEMITSU YOSHIKAZU;HARADA YUI;SAITO SATORU;YAZAKI YUICHIRO;OKAMOTO MASATO;ISHIDAO TAKEFUMI;TELLA, INC;KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION |
发明人 |
YONEMITSU YOSHIKAZU;HARADA YUI;SAITO SATORU;YAZAKI YUICHIRO;OKAMOTO MASATO;ISHIDAO TAKEFUMI |
分类号 |
C12N5/0783;A61K35/14 |
主分类号 |
C12N5/0783 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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