发明名称 |
HUMANIZED ANTIBODY AND PROCESS FOR PREPARING SAME |
摘要 |
A humanized antibody is produced by process comprising the steps of: (a) selecting a specificity determining residue (SDR) of the complementarity determining region (CDR) of murine monoclonal antibody heavy chain and light chain variable regions; and (b) grafting said SDR to at least one of the corresponding amino acid sequences in human antibody variable regions. |
申请公布号 |
US2014121358(A1) |
申请公布日期 |
2014.05.01 |
申请号 |
US201213653481 |
申请日期 |
2012.11.15 |
申请人 |
APROGEN, INC. |
发明人 |
HONG HYO JEONG;MAENG CHEOL YOUNG;YANG GI HYEOK;JANG MEONG HEE;OH MEE SOOK;SONG JIN SOO;JANG YOUNG KUG |
分类号 |
C07K16/18;C07K16/46;C07K16/08 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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