COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS
摘要
The present disclosure provides a composition comprising a GABAA agonist and a GI enzyme inhibitor. The present disclosure also provides a composition comprising (a) a GI enzyme inhibitor and (b) a first drug that interacts with a second drug to produce an adverse effect when the second drug is co-ingested as a GI enzyme-cleavable prodrug with the first drug. Such an interaction can be additive or synergistic.
申请公布号
WO2012122412(A3)
申请公布日期
2014.05.01
申请号
WO2012US28357
申请日期
2012.03.08
申请人
SIGNATURE THERAPEUTICS, INC.;JENKINS, THOMAS E.;STURMER, ALEX GREGORY