FORMATION OF ARRAY OF MEMBRANES AND APPARATUS THEREFOR
摘要
An array of membranes comprising amphipathic moleculesis formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.
申请公布号
WO2014064443(A2)
申请公布日期
2014.05.01
申请号
WO2013GB52766
申请日期
2013.10.23
申请人
OXFORD NANOPORE TECHNOLOGIES LIMITED
发明人
HYDE, JASON ROBERT;BAHAMON, PEDRO MIGUEL ORTIZ;BROWN, CLIVE GAVIN;HERON, ANDREW JOHN;MACKETT, PAUL RAYMOND