ISOQUINOLINE AMIDE DERIVATIVE

摘要

PROBLEM TO BE SOLVED: To provide an excellent prophylactic or therapeutic agent for dementia, integration disorder syndrome or the like, based on serotonine 5-HTreceptor-modulating action.SOLUTION: An isoquinoline derivative, in which a ring group is bonded to the 1-position of an isoquinoline ring and another ring group is bonded to the 7-position of the isoquinoline ring through a bond group having an amide group, has potent 5-HTreceptor-modulating action and excellent pharmacological action based on the action. Thereby, the isoquinoline derivative is useful as a prophylactic or therapeutic agent for dementia, integration disorder syndrome, bipolar disorder or attention-deficit hyperactivity disorder.