SUBSTITUTED SULFONE-CONTAINING TRICYCLIC COMPOUNDS AND USES THEREOF
摘要
<p>The present invention relates to substituted sulfone-containing tricyclic compounds and analogues thereof which inhibit Bak-mediated apoptosis. The invention further relates to pharmaceutical compositions comprising a compound of the present invention and to methods of inhibiting a Bak-mediated apoptotic pathway and Bak-mediated apoptosis in a cell.</p>
申请公布号
WO2014063193(A1)
申请公布日期
2014.05.01
申请号
WO2013AU01229
申请日期
2013.10.23
申请人
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人
KILE, BENJAMIN THOMAS;LESSENE, GUILLAUME LAURENT;HUANG, DAVID CHING SIANG;WATSON, KEITH GEOFFREY;BUI, CHINH THIEN;NGUYEN, THAO LIEN THI;CHAPPAZ, STEPHANE ANDRE
