Antibodies against insulin-like growth factor 1 receptor and uses thereof for the manufacture of pharmaceutical compositions

摘要

An antibody binding to IGF-IR, being of human IgG1 or IgG3 type and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/ or the amount of N-terminal alpha-1,3-galactose is 1% or less has improved properties in antitumor therapy.