发明名称 |
Opioid-ketamine and norketamine codrug combinations for pain management |
摘要 |
The present invention relates to the field of pain management, and more particularly to synergistic codrugs comprising an opioid and ketamine or norketamine which have been combined to form a single chemical codrug entity. When the codrug is administered it produces a synergistic analgesic response to pain. |
申请公布号 |
US8710070(B2) |
申请公布日期 |
2014.04.29 |
申请号 |
US20090934946 |
申请日期 |
2009.03.27 |
申请人 |
HOLTMAN JOSEPH R.;CROOKS PETER A.;CHAKRABORTY UJJWAL;UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
HOLTMAN JOSEPH R.;CROOKS PETER A.;CHAKRABORTY UJJWAL |
分类号 |
A61K31/44;A61K31/35;C07D221/22;C07D405/00 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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