发明名称 NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES
摘要 <p>The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds. These compounds are useful for therapy or prophylaxis in a mammal, and in particular as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.</p>
申请公布号 SG11201400679W(A) 申请公布日期 2014.04.28
申请号 SG11201400679W 申请日期 2012.09.12
申请人 F. HOFFMANN-LA ROCHE AG 发明人 AEBI, JOHANNES;AMREIN, KURT;HORNSPERGER, BENOIT;KNUST, HENNER;KUHN, BERND;LIU, YONGFU;MAERKI, HANS P.;MAYWEG, ALEXANDER V.;MOHR, PETER;TAN, XUEFEI;ZHOU, MINGWEI
分类号 C07D401/04;A61K31/4709;A61P9/12 主分类号 C07D401/04
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