| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to medication for treatment or prevention of disease, which developed on the basis of structural and/or functional, and/or compositional changes of lipids in cell membranes, selected from cancer, vascular diseases, inflammatory diseases, metabolic diseases, obesity and excessive body weight, neurological or neurodegenerative disorders, which represents compound of formula COOR-CHR-(CH)-(CH=CH-CH)-(CH)-CH(I) or its pharmaceutically acceptable salts and derivatives, selected from esters, ethers, alkyl, acyl, phosphate, sulfate, ethyl, methyl or propyl; in which a and c can have independent values from 0 to 7; b can have independent values from 2 to 7, where Ris selected from the following radicals: H, Na, K, CHO, CH-CHO and OPO(O-CH-CH), and Ris selected from the following radicals: OH, OCH, O-CHCOOH, CH, Cl, CHOH, OPO(O-CH-CH), NOH, F, HCOO and N(OCHCH).Invention also relates to application of formula (I) compound and pharmaceutical composition, which contains it.EFFECT: medications, based on claimed compound, are more efficient than medications of preceding level of technology.22 cl, 7 dwg, 16 tbl, 10 ex |
