| 发明名称 |
BISARYLSULFONE AND DIALKYLARYLSULFONE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS |
| 摘要 |
The invention relates to bisarylsulfone and dialkylarylsulfone compounds (e.g., compounds according to any of Formulas (I)-(IX) or compounds (1)-(227) of Tables 4 and 5) useful in treating conditions associated with calcium channel function, and particularly conditions associated with N-type calcium channel activity. The invention also relates to pharmaceutical compositions that include these bisarylsulfone compounds, as well methods for the treatment of conditions such as cardiovascular disease, epilepsy, cancer and pain. |
| 申请公布号 |
US2014113898(A1) |
申请公布日期 |
2014.04.24 |
| 申请号 |
US201113883956 |
申请日期 |
2011.11.04 |
| 申请人 |
PAJOUHESH HASSAN A.;HOLLAND RICHARD;ZHOU YUANXI;ZHU YONGBAO;GRIMWOOD MICHAEL EDWARD;CHAHAL NAVJOT;ZALICUS PHARMACEUTICALS LTD. |
发明人 |
PAJOUHESH HASSAN A.;HOLLAND RICHARD;ZHOU YUANXI;ZHU YONGBAO;GRIMWOOD MICHAEL EDWARD;CHAHAL NAVJOT |
| 分类号 |
C07D487/04;C07C317/32;C07D213/82;C07D231/14;C07D239/28;C07D295/26;C07D471/04 |
主分类号 |
C07D487/04 |
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