发明名称 |
Percutaneous administration device of bisoprolol |
摘要 |
The present invention relates to a percutaneous administration device of bisoprolol, which includes a backing; and a pressure-sensitive adhesive layer containing bisoprolol, which is laminated on one surface of the backing, wherein the maximum value of a release rate of bisoprolol during a period of from immediately after the application on skin until a lapse of 24 hours is 30μg/cm2/hr or less; and wherein the release rate of bisoprolol at the time of a lapse of 24 hours after the application on skin is 10μg/cm2/hr or less. The percutaneous administration device of the present invention is reduced in the skin irritation during the application, especially at the time of peeling, and is capable of persistently administrating a therapeutically or preventively effective amount of bisoprolol into a living body. |
申请公布号 |
US8703178(B2) |
申请公布日期 |
2014.04.22 |
申请号 |
US20080528194 |
申请日期 |
2008.03.06 |
申请人 |
IWAO YOSHIHIRO;MATSUOKA KENSUKE;OKADA KATSUHIRO;MINAMI KUNIHIRO;YUASA SHUICHIRO;NITTO DENKO CORPORATION;TOA EIYO LTD. |
发明人 |
IWAO YOSHIHIRO;MATSUOKA KENSUKE;OKADA KATSUHIRO;MINAMI KUNIHIRO;YUASA SHUICHIRO |
分类号 |
A61K9/70;A61K31/138;A61P9/00 |
主分类号 |
A61K9/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|