| 发明名称 |
Modified lecithin-cholesterol acyltransferase enzymes |
| 摘要 |
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide. |
| 申请公布号 |
US8703926(B1) |
申请公布日期 |
2014.04.22 |
| 申请号 |
US201213439428 |
申请日期 |
2012.04.04 |
| 申请人 |
ZHOU MINGYUE;SHEN WENYAN;SHAN BEI;SCHWARZ MARGRIT;MEININGER DAVID PARK;BOONE TOM;AMGEN INC. |
发明人 |
ZHOU MINGYUE;SHEN WENYAN;SHAN BEI;SCHWARZ MARGRIT;MEININGER DAVID PARK;BOONE TOM |
| 分类号 |
C07H21/04;C12N9/10;C12P21/02 |
主分类号 |
C07H21/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
