发明名称 |
SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF |
摘要 |
<p>The present invention provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount, activity, or expression of the target nucleic acid in a cell. In certain embodiments, hybridization results in selective modulation of the amount, activity, or expression of a target Huntingtin gene or Huntingtin transcript in a cell.</p> |
申请公布号 |
CA2887884(A1) |
申请公布日期 |
2014.04.17 |
申请号 |
CA20132887884 |
申请日期 |
2013.10.11 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
OESTERGAARD, MICHAEL;SETH, PUNIT P.;SWAYZE, ERIC E. |
分类号 |
C12N15/113;A61K31/7115;A61K31/7125;A61P25/14;A61P25/28;C07H21/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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