LIQUID PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDE
摘要
<p>The invention concerns a liquid pharmaceutical composition comprising: A Factor VIIa polypeptide; A buffering agent suitable for keeping pH in the range of from about 5.5 to about 8.5; and An active site stabilizing agent, which is a compound exhibiting a Fit value >0 in the pharmacophore model described by the Pharmacophore Model and Methods Description when using the parameter settings described by the Pharmacophore Model and Methods Description, or a pharmaceutically acceptable salt of said compound.</p>
申请公布号
WO2014057068(A1)
申请公布日期
2014.04.17
申请号
WO2013EP71224
申请日期
2013.10.10
申请人
NOVO NORDISK HEALTH CARE AG
发明人
GANDHI, PRAFULL S.;HENRIKSEN, ANETTE;ROSSMEISL, CHARLOTTE C.;RASMUSSEN, HANNE BENEDICTE;ANDERSEN, HENRIK SUNE;BJØRN, SØREN E.;NØRSKOV-LAURITSEN, LEIF