REDUCING DISPERSION DUE TO VIAS IN PLANAR MICROFLUIDIC SEPARATION DEVICES

摘要

A planar microfluidic chemical separation device includes a separation channel that is located in the plane of the device. The device also includes one or more vias situated perpendicular to the separation channel. The vias extends between the separation channel and an outer surface of the substrate for fluid communication with the separation channel. The vias have cross-sectional areas that are substantially less than a cross-sectional area of a first region of the separation channel to inhibit band-broadening caused by passage of a sample band through the one or more vias.