| 摘要 |
A compound represented by formula (I) or a salt thereof, which has a potent Raf inhibitory activity. In formula (I), R1 represents an optionally substituted C1-6 alkyl, etc.; X represents—O—or—NR2—(wherein R2 represents a hydrogen atom or a C1-6 alkyl); Y represents a group represented by formula 2 (2i or 2ii) (wherein ring A represents an optionally substituted benzene ring; Z represents a group represented by (1)—NR3CO—W1—, (2)—NR3CO—W1—O—, (3)—NR3CO—W1—O—W2—, (4)—NR3CO—W1—S—, (5)—NR3CO—W1—NR4—, (6)—NR3COO—, (7)—NR3COO—W1—, (8)—NR3CO—CO—, or (9)—NR3CONR4—(wherein R3 and R4 each represents a hydrogen atom, etc., and W1 and W2 each represents an optionally substituted C1-6 alkylene, etc.); and R5 represents an optionally substituted five- or six-membered ring group. |
