发明名称 |
Substituted phenylether-thienopyridone compounds with antibacterial activity |
摘要 |
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-Clostridium difficile agents. |
申请公布号 |
US8697720(B2) |
申请公布日期 |
2014.04.15 |
申请号 |
US20070853589 |
申请日期 |
2007.09.11 |
申请人 |
GUILES JOSEPH;SUN XICHENG;JANJIC NEBOJSA;STRONG SARAH;CRESTONE, INC. |
发明人 |
GUILES JOSEPH;SUN XICHENG;JANJIC NEBOJSA;STRONG SARAH |
分类号 |
A01N43/42;A61K31/44;C07D215/00;C07D513/02;C07D515/02 |
主分类号 |
A01N43/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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