发明名称 METHOD FOR PREDICTION OF RISK OF PERINATAL PATHOLOGY
摘要 FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynaecology, and also can be used by the doctors of the other areas of medicine. Substance of the method: ultrasonography in pregnant women aims at detecting appendage new growths and diagnosing degree I and II foetal growth retardation (FGR). The symptoms observed enable finding out: preeclampsia, thrombocyte (Tr) and leukocyte (WBC) count in complete blood count, total blood plasma protein by biochemical blood assay, A coagulogramma shows activated partial thromboplastin time (APTT) and thrombocyte (Tr) count. A vaginal secretion is sampled and analysed for cytomegalovirus (CMV) by a polymerase chain reaction. That is followed by calculating a prognostic index R by formula R=-1.59K1-0.96K2+1.33K3-0.6K4-1K5-0.009K6+0.003K7-0.03K8-0.007K9-0.04K10+4.78, wherein K1 is appendage new growths - yes - 1, no - 0; K2 - cytomegalovirus - yes - 1, no - 0; K3 - preeclampsia - yes - 1, no - 0; K4 - degree I foetal growth retardation - yes - 1, no - 0; K5 - degree II foetal growth retardation - yes - 1, no - 0; K6 - WBC - leukocyte count in complete blood count (*10/mm); K7 - Tr - thrombocyte count in complete blood count (*10/mm); K8 - total protein - total protein in biochemical blood assay (g/l); K9 - Tr - thrombocyte count in the coagulogram (*10/mm); K10 - APTT - activated partial thromboplastin time (sec) in the coagulogram; 4.78 is a constant. If R is less than 0, a risk of a perinatal pathology is stated. R exceeding 0 enables stating no risk of a perinatal pathology.EFFECT: improved prediction procedure.2 ex
申请公布号 RU2512808(C2) 申请公布日期 2014.04.10
申请号 RU20120122788 申请日期 2012.06.01
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "URAL'SKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT OKHRANY MATERINSTVA I MLADENCHESTVA" MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII (FGBU "NII OMM" MINZDRAVSOTSRAZVITIJA ROSSII) 发明人 SIVOV EVGENIJ VASIL'EVICH;KOVALEV VLADISLAV VIKTOROVICH;MAZUROV ALEKSANDR DANILOVICH
分类号 G01N33/53;G01N33/48 主分类号 G01N33/53
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