发明名称 CELL THERAPY FOR CHRONIC STROKE
摘要 A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells in at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at−170° C. before use. Also disclosed are methods of improving speech, cognitive, sensory, and motor function in a person who has experienced brain damage which interferes with function by administering a sterile composition of a sufficient number of neuronal cells or neural stem cells to the damaged area. Also disclosed is a method of replacing central nervous cells lost to neurodegenerative disease, trauma, ischemia or poisoning.
申请公布号 US2014099286(A1) 申请公布日期 2014.04.10
申请号 US201314037990 申请日期 2013.09.26
申请人 SANBERG PAUL R.;KONDZIOLKA DOUGLAS;MCGROGAN MICHAEL P.;SNABLE GARY L.;UNIVERSITY OF SOUTH FLORIDA 发明人 SANBERG PAUL R.;KONDZIOLKA DOUGLAS;MCGROGAN MICHAEL P.;SNABLE GARY L.
分类号 A61K35/30;A61K48/00 主分类号 A61K35/30
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